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产品详情
操作说明
注意事项
Product Information
|
Description |
WDR59 rabbit polyclonal |
|
Protein full name |
GATOR complex protein WDR59 |
|
Synonyms |
CUL4- and DDB1-associated WDR protein 12, WD repeat-containing protein 59, Wdr59, Cdw12 |
|
Immunogen |
Recombinant protein corresponding to Mouse WDR59 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
112 kDa |
|
Observed MW. |
112 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, muscle |
Background
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
Images
|
|
Western blot analysis of WDR59 (GB111121) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室