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Product Information
Description |
S100A11 rabbit polyclonal |
Protein full name |
Protein S100-A11 |
Synonyms |
Calgizzarin, Endothelial monocyte-activating polypeptide, EMAP, Rotein S100-C, S100a11, S100 calcium-binding protein A11, S100c |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100A11 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
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Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1: 500-1: 1500 |
spleen, kidney, lung |
IF |
Human, Mouse, Rat |
1: 400-1: 1000 |
spleen, kidney, lung |
Background
S100A11 (also known as S100C or calziggarin), is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs . S100 proteins involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. First discovered in 1989, S100A11 has since been proposed to have direct biological functions in an assortment of physiological processes such as endo and exocytosis, regulation of enzyme activity, cell growth and regulation, apoptosis and inflammation (PMID: 15241500). Chromosomal rearrangements and altered expression of S100A11 have been implicated in tumor metastasis. This S100A11 antibody (10237-1-AP) has also been instrumental in investigations into S100A11’s role in the development of brain tumors in tuberous sclerosis complex (TSC) patients .
Images
Immunohistochemistry analysis of paraffin-embedded mousespleen using S100A11 (GB111080) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using S100A11 (GB111080) at dilution of 1: 1000 | |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using S100A11 (GB111080) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded rat lung using S100A11 (GB111080) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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