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Anti -PTPN12 Rabbit pAb
价格：
在线咨询
货号：
DRF101198
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
H/M/R,H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
PTPN12 rabbit polyclonal |
|
Protein full name |
Tyrosine-protein phosphatase non-receptor type 12 |
|
Synonyms |
Protein-tyrosine phosphatase P19, Ptpn12, MPTP-PEST, P19-PTP |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PTPN12 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
88 kDa |
|
Observed MW. |
110 kDa |
|
Subcellular location |
|
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Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 800 |
lung, ovary, testis |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 3000 |
lung cancer, brain, ovary, lung |
|
IF |
Human, Mouse, Rat |
1: 500-1: 2000 |
lung cancer, brain, ovary, lung |
Background
The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.
Images
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Western blot analysis of PTPN12 (GB111076) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using PTPN12 (GB111076) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using PTPN12 (GB111076) at dilution of 1:2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse ovary using PTPN12 (GB111076) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using PTPN12 (GB111076) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using PTPN12 (GB111076) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室