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产品详情
操作说明
注意事项
Product Information
|
Description |
PTMA rabbit polyclonal |
|
Protein full name |
Prothymosin alpha |
|
Synonyms |
N-terminally processed, Thymosin alpha, Ptma, Prothymosin alpha like 1 protein |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PTMA |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus |
|
Uniprot ID |
P26350, P06302 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1:750-1:1500 |
colon, lung |
|
IF |
Human, Mouse, Rat |
1:500-1:2000 |
colon, lung |
Background
Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using PTMA (GB111050) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat lung using PTMA (GB111050) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室