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Product Information
Description |
Desmin rabbit polyclonal |
Protein full name |
Desmin |
Synonyms |
DES, CSM1, CSM2, LGMD2R, desmin |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse desmin |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 54KDa |
Observed MW. | 55KDa |
Subcellular location | Cytoplasm,Cell membrane |
Uniprot ID | P31001,P48675 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 1000-1: 2000 |
Heart |
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
Heart,skeletal muscle |
IF |
Human, Mouse, Rat |
1: 500-1: 2000 |
Heart,skeletal muscle |
Background
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures . May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.
Images
|
Western blot analysis of Desmin (GB11081) at dilution of 1:1000. Lane 1:Mouse heart tissue lysate Lane 2:Mouse heart tissue lysate Lane 3:Mouse heart tissue lysate Lane 4:Rat heart tissue lysate |
|
Immunohistochemistry analysis of parafffin-embedded mouse heart using Desmin (GB11081) at dilution of 1:1800 |
|
Immunohistochemistry analysis of parafffin-embedded rat skeletal muscle using Desmin (GB11081) at dilution of 1:1800 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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