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产品详情
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注意事项
Product Information
| Description | Collagen I rabbit polyclonal |
| Protein full name | Collagen alpha-1(I) chain |
| Synonyms |
COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse COL1A1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 139KDa |
| Observed MW. | 110-130KDa |
| Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1:500-1:1000 |
KB cell,liver cancer,lung,kidney |
Background
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Images
|
|
Western blot analysis of CollagenI (GB11022-2) at dilution of 1:1000. Lane 1:Hela cell lysate Lane 2:HepG2 cell lysate Lane 3:KB cell lysate Lane 4:Human liver cancer lysate Lane 5:Mouse lung tissue lysate Lane 6:Rat lung tissue lysate Lane 7:Rat kidney tissue lysate
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
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