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Anti -BAX Rabbit pAb

价格: 在线咨询
货号:
DRF10146
产品规格:
100 μL
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项


Product Information



Description Bax rabbit polyclonal
Protein full name Apoptosis regulator Bax
Synonyms BCL2 Associated X Protein ,Bcl-2-Like Protein 4,BCL2L4,Bcl2-L-4
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse Bax
Isotype IgG
Purity Affinity purification
Predicted MW.

21 kDa

Observed MW. 21  kDa
Uniprot ID Q07812,Q07813,Q63690




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1:500-1:1000

Hela,HepG2,colon cancer,liver cancer




Background



Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.




Images



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Western blot analysis of Bax (GB11007) at dilution of 1:1000.

Lane 1:Hela cell lysate

Lane 2:HepG2 cell lysate

Lane 3:Human colon cancer lysate

Lane 4:Human liver cancer lysate

Lane 5:Human breast cancer lysate

Lane 6:Human nasopharyngeal cancer tissue lysate

Lane 7: KB cell lysate

Lane 8:SP20 cell lysate

Lane 9:PC12 cell lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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