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产品详情
操作说明
注意事项
Product Information
|
Description |
KDS rabbit polyclonal antibody |
|
Protein full name |
Serine/threonine-protein kinase TAO3 |
|
Synonyms |
CTCL-associated antigen HD-CL-09, hKFC-A, Dendritic cell-derived protein kinase, DPK, JNK/SAPK-inhibitory kinase, JIK, KDS, Jun kinase-inhibitory kinase, TAOK3, MAP3K18 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human KDS |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane, Cytoplasm |
|
Uniprot ID |
Q9H2K8 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human |
1: 500-1: 1000 |
breast cancer, colon cancer |
Background
TAOK3 (Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated.
Images
|
|
Immunohistochemistry of paraffin embedded human breast cancer using TAOK3at dilution of 1:550 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human colon cancer using TAOK3 at dilution of 1:550 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室