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Anti -MEK2 Rabbit pAb
价格：
在线咨询
货号：
KT012258
产品规格：
100ul
Applications：
WB|IHC/IF
Species：
H/M/R,M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
MEK2 rabbit polyclonal antibody |
|
Protein full name |
Dual specificity mitogen-activated protein kinase kinase 2 |
|
Synonyms |
MAP kinase kinase 2, Prkmk2 ,Mek2, Mkk2, Map2k2, ERK activator kinase 2, MAPK/ERK kinase 2, MAPKK 2, PRKMK 2, PRKMK2 V |
|
Immunogen |
Recombinant protein corresponding to Mouse MEK2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
44 kDa |
|
Observed MW. |
48 kDa |
|
Uniprot ID |
P36507, Q63932, P36506 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, brain |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 2000 |
brain, lung, spleen |
Background
MAP kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.
Images
|
Western blot analysis of MEK2 at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (350x lens) |
|
Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat brain using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat lung using MEK2 at dilution of 1: 2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat spleen using MEK2 at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室