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Anti -Exportin 4/XPO4 Rabbit pAb
价格：
在线咨询
货号：
KT012167
产品规格：
100ul
Applications：
WB
Species：
M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Exportin 4/XPO4 rabbit polyclonal antibody |
|
Protein full name |
Exportin-4 |
|
Synonyms |
Exp4, Xpo4, Kiaa1721 |
|
Immunogen |
Recombinant protein corresponding to Mouse Exportin 4/XPO4 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
130 kDa |
|
Observed MW. |
130 kDa |
|
Uniprot ID |
Q9ESJ0 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 1000-1: 2000 |
thymus |
Background
XPO4 belongs to a large family of karyopherins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments . In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Images
|
Western blot analysis of Xpo4 (GB112617) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室