服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
产品详情
操作说明
注意事项
Product Information
|
Description |
RB-1 rabbit polyclonal antibody |
|
Protein full name |
Retinoblastoma-associated protein |
|
Synonyms |
pRb, Rb, pp105, Rb1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse RB-1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus |
|
Uniprot ID |
P13405, P33568 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 2500 |
brain, kidney, lung, Skeletal muscle |
Background
RB1 belongs to the retinoblastoma protein family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
Images
|
|
Immunohistochemistry of paraffin embedded mouse brain using RB1 (GB111111) at dilution of 1:700 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse kidney using RB1 (GB111111) at dilution of 1:700 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse Skeletal muscle using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:700 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat kidney using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat lung using RB1 (GB111111) at dilution of 1:700 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse Brain using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse Skeletal muscle using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
Immunofluorescence of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat kidney using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat lung using RB1 (GB111111) at dilution of 1:1400 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室