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Anti -Id1 Rabbit pAb

价格: 在线咨询
货号:
KT012069
产品规格:
100ul
Applications:
IHC/IF
Species:
M/R,M/R
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

Id1 rabbit polyclonal

Protein full name

DNA-binding protein inhibitor ID-1

Synonyms

Inhibitor of DNA binding 1, Inhibitor of differentiation 1, Id1, Id, Id-1, Idb1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Id1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

P20067, P41135




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 800-1: 1600

lung, liver, lymph, colon

IF

Mouse, Rat

1: 1500-1: 3000

testis, lung




Background


ID (inhibitor of DNA binding) proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID1 proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID proteins contribute to cell growth, senescence, differentiation, and angiogenesis. Inhibitor of differentiation or DNA binding-1 (ID1) interacts with the trans activation domain of p65 (p65TAD) both in vitro and in vivo.




Images


Immunohistochemistry analysis of paraffin-embedded mouse lung using Id1 (GB111182) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded rat lung using Id1 (GB111182) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded mouse lymph using Id1 (GB111182) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded rat lymph using Id1 (GB111182) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded mouse liver using Id1 (GB111182) at dilution of 1: 1500


Immunohistochemistry analysis of paraffin-embedded rat colon using Id1 (GB111182) at dilution of 1: 1500

Immunofluorescent analysis of paraffin-embedded mouse testis using Id1 (GB111182) at dilution of 1: 1500

Immunofluorescent analysis of paraffin-embedded rat lung using Id1 (GB111182) at dilution of 1: 1500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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