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Anti -Osteoprotegerin Rabbit pAb
价格：
在线咨询
货号：
KT012052
产品规格：
100 μL
Applications：
IHC/IF
Species：
M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
Osteoprotegerin rabbit polyclonal antibody |
|
Protein full name |
Tumor necrosis factor receptor superfamily member 11B |
|
Synonyms |
TNFRSF11B, OCIF, OPG, PDB5, TR1, tumor necrosis factor receptor superfamily member 11b, TNF receptor superfamily member 11b |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
O08712, O08727 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 100-1: 400 |
bone |
Background
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Images
|
Immunohistochemistry of paraffin embedded mouse bone using OPG (GB11151) at dilution of 1:200 (100x lens) |
|
Immunohistochemistry of paraffin embedded rat bone using OPG (GB11151) at dilution of 1:200 (100x lens) |
|
|
Immunofluorescence of paraffin embedded mouse bone using OPG (GB11151) at dilution of 1:100 (100x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室