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产品详情
操作说明
注意事项
Product Information
|
Description |
Inhibin alpha rabbit polyclonal antibody |
|
Protein full name |
Inhibin alpha chain |
|
Synonyms |
Inha, A inhibin subunit precursor, IHA, INHA, Inhibin alpha chain precursor |
|
Immunogen |
Recombinant protein corresponding to Human Inhibin alpha |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
P17490 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Rat |
1: 900-1: 1800 |
brain, lung, spleen |
Background
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Images
|
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Immunohistochemistry of paraffin embedded rat brain using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens) |
|
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Immunohistochemistry of paraffin embedded rat lung using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens) |
|
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Immunohistochemistry of paraffin embedded rat spleen using Inhibin-Alpha (GB111221) at dilution of 1:900 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室