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Anti -Insulin degrading enzyme / IDE Rabbit pAb
价格：
在线咨询
货号：
KT012025
产品规格：
100 μL
Applications：
WB
Species：
H/M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
IDE rabbit polyclonal antibody |
|
Protein full name |
Insulin-degrading enzyme |
|
Synonyms |
Insulin protease, Insulinase, Insulysin, Ide, FLJ35968, Abeta-degrading protease |
|
Immunogen |
Recombinant protein corresponding to Mouse IDE |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
118 kDa |
|
Observed MW. |
120 kDa |
|
Uniprot ID |
P14735, Q9JHR7, P35559 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, skeletal muscle, colon |
Background
IDE(Insulin-degrading enzyme) belongs to the peptidase M16 family. It is also known as insulysin and is a neutral metallopeptidase that Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.The reduction of IDE expression may be a risk factor for AD, and that IDE may interact with APOE status to affect beta-amyloid metabolism.
Images
|
|
Western blot analysis of IDE (GB111387) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室