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产品详情
操作说明
注意事项
Product Information
|
Description |
AUH rabbit polyclonal antibody |
|
Protein full name |
Methylglutaconyl-CoA hydratase, mitochondrial |
|
Synonyms |
AU-specific RNA-binding enoyl-CoA hydratase, AU-binding enoyl-CoA hydratase, muAUH, Itaconyl-CoA hydratase, Auh |
|
Immunogen |
Recombinant protein corresponding to Mouse AUH |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
33 kDa |
|
Observed MW. |
28 kDa |
|
Uniprot ID |
Q9JLZ3, F1LU71 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, brain, kidney, liver |
Background
The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity.
Images
|
Western blot analysis of AUH (GB111521) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室