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Anti -kynurenine 3-monooxygenase Rabbit pAb
价格：
在线咨询
货号：
KT011993
产品规格：
100ul
Applications：
WB|IHC/IF
Species：
M/R,M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
KMO rabbit polyclonal antibody |
|
Protein full name |
Kynurenine 3-monooxygenase |
|
Synonyms |
Kynurenine 3-hydroxylase, KMO |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse KMO |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
55 kDa |
|
Observed MW. |
55 kDa |
|
Uniprot ID |
O15229, Q91WN4, O88867 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
stomach, heart, brain, cartilage |
|
IHC/IF |
Human, Rat |
1: 1000-1: 6000 |
colon, esophagus, liver cancer, lung |
Background
KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Images
|
|
Western blot analysis of KMO (GB111295) at dilution of 1: 500 |
|
|
Immunohistochemistry of paraffin embedded human esophagus using KMO (GB111295) at dilution of 1: 900 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human liver cancer using KMO (GB111295) at dilution of 1: 900 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human colon using KMO (GB111295) at dilution of 1: 1800 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat lung using KMO (GB111295) at dilution of 1: 1800 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室