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产品详情
操作说明
注意事项
Product Information
|
Description |
FRK rabbit polyclonal antibody |
|
Protein full name |
Tyrosine-protein kinase FRK |
|
Synonyms |
Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, FRK, Bsk, Iyk |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse FRK |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
59 kDa |
|
Observed MW. |
57 kDa |
|
Uniprot ID |
P42685, Q922K9 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
kidney, colon |
Background
The FRK is a non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Images
|
|
Western blot analysis of FRK (GB111299) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室