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Product Information
Description |
c-Jun rabbit polyclonal antibody |
Protein full name |
Transcription factor AP-1 |
Synonyms |
JUN, AP-1, AP1, c-Jun, Jun proto-oncogene, AP-1 transcription factor subunit |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse c-JUN |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus |
Uniprot ID |
P05412, P05627, P17325 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 1000-1: 4000 |
brain, kidney, skin, stomach, testis |
Background
c-Jun
is a protein that in humans is encoded by the JUN gene. c-Jun in
combination with c-Fos, forms the AP-1early response transcription
factor. It was first identified as the Fos-binding protein p39 and only
later rediscovered as the product of the c-jun gene. It is activated
through double phosphorylation by the JNK pathway but has also a
phosphorylation-independent function. c-jun knockout is lethal, but
transgenic animalswith a mutated c-jun that cannot be phosphorylated
(termed c-junAA) can survive.
Images
|
Immunohistochemistry of paraffin embedded human stomach using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse kidney using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
Immunohistochemistry of paraffin embedded rat kidney using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse skin using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
|
Immunofluorescence of paraffin embedded rat brain using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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