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产品详情
操作说明
注意事项
Product Information
|
Description |
ADAMTS1 rabbit polyclonal antibody |
|
Protein full name |
A disintegrin and metalloproteinase with thrombospondin motifs 1 |
|
Synonyms |
ADAMTS1, ADAMTS, METH1. KIAA1346, A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 1, ADAM metallopeptidase with thrombospondin type 1 motif 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human ADAMTS1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
106 kDa |
|
Observed MW. |
110 kDa |
|
Uniprot ID |
P97857, Q9WUQ1 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, brain |
Background
ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs 1), is the founding member of the family of secreted zinc proteases with a multidomain structure. The protein precursor consists of a signal peptide and the following domains: pro, catalytic, disintegrinlike, TS type 1 motif, cysteine rich, spacer and a variable number of thrombospondin type 1 motifs. Based on their substrate specificity, ADAMTS1 and associated family members may be key enzymes in the degradation of cartilage leading to inflammation and arthritis. It is an active protease cleaving alpha 2 macroglobulin, aggrecan and versican. ADAMTS1 is essential for normal growth and the structure and function of the kidneys, adrenal glands and female reproductive organs. It also plays an important role in atherosclerosis.
Images
|
Western blot analysis of ADAMTS1 (GB111011) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室