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Anti -NF2 / Merlin Rabbit pAb
价格：
在线咨询
货号：
KT011895
产品规格：
100ul
Applications：
IHC/IF
Species：
M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
NF2 rabbit polyclonal antibody |
|
Protein full name |
Merlin |
|
Synonyms |
Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomin, Schwannomin, NF2 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse NF2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Cell Membrane, Nucleus |
|
Uniprot ID |
P46662, Q63648 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 3000 |
brain, eye, heart, lung, spleen |
Background
NF2 is the probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
Images
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Immunohistochemistry of paraffin embedded mouse eye using NF2 (GB111285) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse heart using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse spleen using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using NF2 (GB111285) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室