服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
Anti -beta Catenin Rabbit pAb
价格：
在线咨询
货号：
KT011814
产品规格：
100ul
Applications：
WB/IHC/IF
Species：
H/M/R,H/M/R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
beta Catenin rabbit polyclonal antibody |
|
Protein full name |
Catenin beta-1 |
|
Synonyms |
CTNNB1, CTNNB, MRD19, armadillo, catenin beta 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Nucleus, Cell junction |
|
Predicted MW. |
92 kDa |
|
Observed MW. |
92 kDa |
|
Uniprot ID |
P35222, Q02248, Q9WU82 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 2000 |
colon, small intestine, stomach |
Background
β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.
Images
|
|
Western blot analysis of β-catenin (GB11015) at dilution of 1: 500
|
|
Immunohistochemistry of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 1500 (400x lens)
|
|
|
Immunofluorescence of paraffin embedded human colon using β-catenin (GB11015) at dilution of 1: 500 (300x lens) |
|
|
Immunofluorescence of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 500 (200x lens) |
|
|
Immunofluorescence of paraffin embedded mouse small intestine using β-catenin (GB11015) at dilution of 1: 200 (400x lens) |
|
Immunofluorescence of paraffin embedded rat stomach using β-catenin (GB11015) at dilution of 1: 200 (400x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室