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Anti -Myosin light chain 3 Rabbit pAb

价格: 在线咨询
货号:
KT011885
产品规格:
100ul
Applications:
WB/IHC/IF
Species:
M/R,M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Myosin light chain 3 rabbit polyclonal antibody

Protein full name

Myosin light chain 3

Synonyms

Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform, MLC1SB, Myl3, Mlc1v, Mylc,  Myosin light chain 3

Immunogen

Recombinant protein corresponding to Mouse Myosin light chain 3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Predicted MW.

22 kDa

Observed MW.

23 kDa

Uniprot ID

P09542, P16409




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

heart, skeletal muscle

IHC/IF

Mouse, Rat

1: 1500-1: 3000

esophagus, lung, Skeletal muscle




Background


MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.




Images


Western blot analysis of MYL3 (GB111241) at dilution of 1: 500

Immunohistochemistry of paraffin embedded mouse lung using MYL3 (GB111241) at dilution of 1: 3400 (400x lens)

Immunohistochemistry of paraffin embedded mouse skeletal muscle using MYL3 (GB111241) at dilution of 1: 1700 (400x lens)

Immunohistochemistry of paraffin embedded rat esophagus using MYL3 (GB111241) at dilution of 1: 3400 (400x lens)

Immunohistochemistry of paraffin embedded rat skeletal muscle using MYL3 (GB111241) at dilution of 1: 1700 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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