服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
Anti -Villin Rabbit pAb
价格：
在线咨询
货号：
KT011878
产品规格：
100ul
Applications：
WB|IHC/IF
Species：
H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Villin rabbit polyclonal antibody |
|
Protein full name |
Villin-1 |
|
Synonyms |
VIL1, VIL, Villin 1, D2S1471 |
|
Immunogen |
Recombinant protein corresponding to Human Villin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
93 kDa |
|
Observed MW. |
95 kDa |
|
Uniprot ID |
P09327, Q62468 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
small intestine, colon, kidney |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
colon, gall bladder, kidney, small intestine |
Background
Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Images
|
|
Western blot analysis of villin (GB111209) at dilution of 1: 1000 |
|
|
Immunohistochemistry of paraffin embedded human colon using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse kidney using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat gall bladder using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat small intestine using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human colon using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse kidney using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat gall bladder using villin (GB111209) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat small intestine using villin (GB111209) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室