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Anti -NUMB Rabbit pAb

价格: 在线咨询
货号:
KT011783
产品规格:
100ul
Applications:
IHC/IF
Species:
M/R,M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

NUMB rabbit polyclonal

Protein full name

Protein numb homolog

Synonyms

Numb, NUMB, C14orf41, S171, c14_5527, Endocytic adaptor protein, NUMB endocytic adaptor protein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse NUMB

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

Q9QZS3Q2LC84




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 2000

brain

IF

Mouse, Rat

1: 250-1: 500

brain




Background


Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

NUMB (GB11765) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

NUMB (GB11765) at dilution of 1: 1000





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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