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Product Information
Description |
AMF rabbit polyclonal antibody |
Protein full name |
Glucose-6-phosphate isomerase |
Synonyms |
GPI, Autocrine motility factor, AMF, NLK, Neuroleukin, Phosphoglucose isomerase, PGI, PHI, Gpi1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse AMF |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Secreted, Cytoplasm |
Uniprot ID |
P06745, Q6P6V0 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 500-1: 1500 |
brain, spinal cord, spleen |
Background
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse Immune spleen using AMF (GB111160) at dilution of 1: 1000 |
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Immunohistochemistry of paraffin embedded mouse spinal cord using GPI (GB111160) at dilution of 1:500 (400x lens) |
Immunohistochemistry of paraffin embedded mouse spleen using GPI (GB111160) at dilution of 1:500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using GPI (GB111160) at dilution of 1:500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using GPI (GB111160) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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