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产品详情
操作说明
注意事项
Product Information
|
Description |
AFG3L2 rabbit polyclonal antibody |
|
Protein full name |
AFG3-like protein 2 |
|
Synonyms |
AFG3 like protein 2, AFG3L2, Paraplegin like protein, SCA28, Spinocerebellar ataxia 28, AFG3 ATPase family gene 3 like 2 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse AFG3L2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
90 kDa |
|
Observed MW. |
90 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
liver, brain, kidney |
Background
AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. Human AFG3L2 is an 80-kDa protein encoded by a 17-exon gene and highly and selectively expressed in human cerebellar Purkinje cells and it can exsit as a truncated 65 kDa protein. Defects in AFG3L2 are the cause of spinocerebellar ataxia type 28 (SCA28) and spastic ataxia autosomal recessive type 5 (SPAX5).
Images
|
Western blot analysis of AFG3L2 (GB113859) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室