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Product Information
Description |
BDNF rabbit polyclonal antibody |
Protein full name |
Brain-derived neurotrophic factor |
Synonyms |
BDNF, brain-derived neurotrophic factor, ANON2, BULN2, Brain-derived neurotrophic factor, Brain derived neurotrophic factor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse BDNF |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
28 kDa |
Observed MW. |
18 kDa |
Uniprot ID |
P21237, P23363 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, cerebellum, hippocampus |
IHC/IF |
Mouse, Rat |
1: 100-1: 200 |
brain, hippocampus |
Background
Brain-derived neurotrophic factor, also known as BDNF, is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor. Neurotrophic factors are found in the brain and the periphery. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. In the brain, it is active in the hippocampus, cortex, and basal forebrain—areas vital to learning, memory, and higher thinking. It is also expressed in the retina, motor neurons, the kidneys, saliva, and the prostate.
Images
|
Western blot analysis of BDNF (GB11559) at dilution of 1: 500 |
Immunohistochemistry analysis of paraffin-embedded mouse brain using BDNF (GB11559) at dilution of 1: 200 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using BDNF (GB11559) at dilution of 1: 200 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse hippocampus using BDNF (GB11559) at dilution of 1: 200 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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