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Anti -Myelin Protein Zero Rabbit pAb

价格: 在线咨询
货号:
KT011585
产品规格:
100 μL
Applications:
WB
Species:
M/R
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

Myelin Protein Zero rabbit polyclonal antibody

Protein full name

Myelin protein P0

Synonyms

Mpz, Myelin protein P0, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0, Myelin protein zero, CHN2

Immunogen

Recombinant protein corresponding to Mouse Myelin Protein Zero

Isotype

IgG

Purity

Affinity purification

Predicted MW.

28 kDa

Observed MW.

28 kDa

Uniprot ID

P27573, P06907



Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

spinal cord



Background


MPZ (myelin protein zero), also known as P0, a transmembrane glycoprotein (30 kDa) is a member of the immunoglobulin super gene family. Synthesized by myelin-forming Schwann cells, MPZ is the major structural protein component of myelin in the peripheral nervous system. It is involved in formation and maintenance of compact myelin, and plays a role in the creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. More than 120 mutations detected in the gene of MPZ cause various forms of hereditary neuropathy, which include Charcot-Marie-Tooth disease type 1B (CMT1B), CMT2, Dejerine-Sottas syndrome (DSS), and congenital hypomyelination neuropathy (CHN).




Images


Picture 1.png

Western blot analysis of MPZ (GB111237) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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