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产品详情
操作说明
注意事项
Product Information
|
Description |
CBLN2 rabbit polyclonal antibody |
|
Protein full name |
Cerebellin-2 |
|
Synonyms |
Cbln2, Cerebellin 2 Precursor |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CBLN2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
Q8IUK8, Q8BGU2, P98087 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1: 300-1: 600 |
brain |
Background
Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1.
Images
|
Immunohistochemistry of paraffin embedded human brain using CBLN2 (GB111673) at dilution of 1:300 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室