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Anti -Neurofilament heavy polypeptide Mouse mAb

价格: 在线咨询
货号:
KT011606
产品规格:
100ul
Applications:
WB
Species:
M
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Neurofilament heavy polypeptide mouse monoclonal

Protein full name

Neurofilament heavy polypeptide

Synonyms

NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, Nefh, Kiaa0845, Nfh, NF200, NF

Immunogen

Recombinant protein corresponding to

Mouse NF200

Isotype

IgG2a

Purity

Affinity purification

Predicted MW.

117 kDa

Observed MW.

200 kDa

Uniprot ID

P19246




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 1000-1: 2000

brain, hippocampus, cerebellum




Background


NEFH (NF200), also named as KIAA0845 and NFH, belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10 nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody can recognize both NEFH and NEFM.




Images


图片 1.png

Western blot analysis of NF200 (GB12141) 

at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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