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Product Information
Description |
SOX10 rabbit polyclonal antibody |
Protein full name |
Transcription factor SOX-10 |
Synonyms |
Sox10, SOX10, DOM, PCWH, WS2E, WS4, WS4C, SRY-box 10 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SOX10 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Uniprot ID |
Q04888, O55170 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 500-1: 4000 |
brain, heart, small intestine |
Background
Transcription factor SOX-10 encoded by the SOX10 gene is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. In melanocytic cells there is evidence that SOX10 gene expression may be regulated by MITF.
Images
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Immunohistochemistry of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse heart using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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