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产品详情
操作说明
注意事项
Product Information
|
Description |
GAD1 rabbit polyclonal antibody |
|
Protein full name |
Glutamate decarboxylase 1 |
|
Synonyms |
Gad1, GAD1, CPSQ1, GAD, SCP, glutamate decarboxylase 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse GAD1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
67 kDa |
|
Observed MW. |
67 kDa |
|
Uniprot ID |
P48318, P18088 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, cerebellum |
Background
Glutamate decarboxylase 1 (brain, 67kDa) (GAD67), also known as GAD1, is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. This enzyme is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.
Images
|
Western blot analysis of GAD67 at dilution of 1: 500
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
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