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Anti -GABA A Receptor alpha 1 Rabbit pAb

价格: 在线咨询
货号:
KT011495
产品规格:
100 μL
Applications:
IHC/IF
Species:
H,M,R
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

GABA A Receptor alpha 1 rabbit polyclonal antibody

Protein full name

Gamma-aminobutyric acid receptor subunit alpha-1

Synonyms

Gabra1, GABRA1, ECA4, EIEE19, EJM, EJM5, gamma-aminobutyric acid type A receptor alpha1 subunit, GABA A Receptor alpha 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GABA A Receptor alpha 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane, Secreted

Uniprot ID

P62812




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 300-1: 1500

brain, cerebellum, glioblastoma multiforme




Background


Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.




Images



Immunohistochemistry of paraffin embedded human brain using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded mouse brain using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded human glioblastoma multiforme using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded mouse cerebellum using GABRA1 (GB11716) at dilution of 1:600

Immunohistochemistry of paraffin embedded rat cerebellum using GABRA1 (GB11716) at dilution of 1:600




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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