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Product Information
Description |
NMDAR1 rabbit polyclonal antibody |
Protein full name |
Glutamate receptor ionotropic, NMDA 1 |
Synonyms |
GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane, Cell junction |
Uniprot ID |
P35438 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 100-1: 500 |
brain, cerebral infarction, epencephalon |
Background
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
Images
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Immunohistochemistry of paraffin embedded mouse brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
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Immunofluorescence of paraffin embedded mouse cerebral infarction using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
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Immunofluorescence of paraffin embedded mouse epencephalon using NMDAR1 (GB11144) at dilution of 1:100 (400x lens)
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