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产品详情
操作说明
注意事项
Product Information
|
Description |
TLR4 rabbit polyclonal |
|
Protein full name |
Toll-like receptor 4 |
|
Synonyms |
TLR4, ARMD10, CD284, TLR-4, TOLL, toll like receptor 4 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TLR4. |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
95 KDa |
|
Observed MW. |
95 KDa |
|
Subcellular location |
Membrane |
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, lung, thymus |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
immune spleen |
|
IF |
Human, Mouse, Rat |
1: 300-1: 1000 |
tonsil, septic spleen, lymph node, spleen |
Background
A member of the toll-like receptor (TLR) family, which plays a fundamental
role in pathogen recognition and activation of innate immunity. It
cooperates with LY96 (also referred as MD-2) and CD14 to mediate
in signal transduction events induced by lipopolysaccharide (LPS) found
in most gram-negative bacteria. Mutations in this gene have been
associated with differences in LPS responsiveness. TLR4 signaling
responds to signals by forming a complex using an extracellular
leucine-rich repeat domain (LRR) and an intracellular toll/interleukin-1
receptor (TIR) domain.
Images
|
Western blot analysis of TLR4 (GB11519) at dilution of 1:1000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse immune spleen using TLR4 (GB11519) at dilution of 1:1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat immune spleen using TLR4 (GB11519) at dilution of 1:1000 |
|
Immunofluorescent analysis of paraffin-embedded human tonsil using TLR4 (GB11519) at dilution of 1:1000 |
|
Immunofluorescent analysis of paraffin-embedded mouse septic spleen using TLR4 (GB11519) at dilution of 1:1000 |
|
Immunofluorescent analysis of paraffin-embedded rat septic spleen using TLR4 (GB11519) at dilution of 1:1000
|
|
Immunofluorescent analysis of paraffin-embedded rat lymph node using TLR4 (GB11519) at dilution of 1:1000 |
|
Immunofluorescent analysis of paraffin-embedded rat spleen using TLR4 (GB11519) at dilution of 1:1000
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室