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产品详情
操作说明
注意事项
Product Information
|
Description |
Dectin-1 rabbit polyclonal |
|
Protein full name |
C-type lectin domain family 7 member A |
|
Synonyms |
Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CD369, Clec7a, Bgr, Clecsf12, Dectin1 |
|
Immunogen |
Recombinant protein corresponding to Mouse Dectin-1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
27 kDa |
|
Observed MW. |
38 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, thymus, liver |
Background
CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response.
Images
|
|
Western blot analysis of Dectin-1 (GB111816)
at dilution of 1: 1000 Lane 1: U2OS cell lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse thymus tissue lysate Lane 4: Mouse liver tissue lysate Lane 5: Rat thymus tissue lysate Lane 6: Rat liver tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室