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产品详情
操作说明
注意事项
Product Information
| Description |
Fas mouse monoclonal |
| Protein full name |
Tumor necrosis factor receptor superfamily member 6 |
|
Synonyms |
FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse FAS |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Cell membrane,Secrete |
| Uniprot ID |
Applications
| Applications |
IHC,IF |
| Species |
Human,Mouse |
| Dilution |
1:200-1:800 |
| Positive tissue |
Gallbadder,colon |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human gallbladder using FAS (GB12089) at dilution of 1:200 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using FAS (GB12089) at dilution of 1:400 |
|
Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS (GB12089) at dilution of 1:400 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室