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Product Information
Description |
PD-1 rabbit polyclonal |
Protein full name |
Programmed cell death protein 1 |
Synonyms |
PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1, Programmed cell death 1 |
Immunogen |
Recombinant protein corresponding to Mouse PD-1 |
Isotype |
IgG |
Predicted MW. |
32 kDa |
Observed MW. |
52 kDa |
Purity |
Affinity purification |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse |
1: 1000-1: 2000 |
inflammatory spleen, inflammatory lung, inflammatory lymph node |
Background
CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Images
|
Western blot analysis of PD-1 (GB11338) at dilution of 1: 1000. Lane 1: Raw264.7 cell lysate Lane 2: Mouse inflammatory spleen tissue lysate Lane 3: Mouse inflammatory lung tissue lysate Lane 4: Mouse inflammatory lymph node tissue lysate
|
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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