服务热线
400-1016-218
全国统一服务热线
400-1016-218
科研好帮手 专业生产商
本公司产品仅供科研使用
英文名称: Anti-TMEM256 rabbit polyclonal antibody
别 名: transmembrane protein 256; C17orf61
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: TMEM256
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
TMEM256, also known as C17orf61, C17orf61 (chromosome 17 open reading frame 61) is a 113 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
Applications: |
ELISA, IHC |
Name of antibody: |
TMEM256 |
Immunogen: |
Fusion protein of human TMEM256 |
Full name: |
transmembrane protein 256 |
Synonyms: |
C17orf61 |
SwissProt: |
Q8N2U0 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer and Human liver cancer |
IHC Recommend dilution: |
25-100 |
合肥万物生物科技有限公司
客服热线:400-1016-218
QQ:355185756
地址:安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室