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产品详情
操作说明
注意事项
Product Information
|
Description |
DKK2 rabbit polyclonal antibody |
|
Protein full name |
Dickkopf-related protein 2 |
|
Synonyms |
Dickkopf-2, Dickkopf related protein 2, DKK-2, DKK2, hDkk 2, mDkk-2 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse DKK2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
28 kDa |
|
Observed MW. |
28 kDa |
|
Uniprot ID |
Q9QYZ8 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse |
1: 1000-1: 2000 |
kidney, heart, lung |
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Images
|
Western blot analysis of DKK2 (GB113829) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室