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Anti -Artemin Rabbit pAb

价格: 在线咨询
货号:
KT011827
产品规格:
100 μL
Applications:
IHC
Species:
R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Artemin rabbit polyclonal

Protein full name

Artemin

Synonyms

Artn, Enovin, EVN, NBN, Neublastin, Neurotrophic factor

Immunogen

Recombinant protein corresponding to

Mouse Artemin

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

Q6AYE8




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 1000-1: 2000

cerebellum, striatum




Background


This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. 




Images


Immunohistochemistry analysis of paraffin-embedded rat cerebellum using 

Artemin (GB113164) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat striatum using 

Artemin (GB113164) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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