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产品详情
操作说明
注意事项
Product Information
|
Description |
Artemin rabbit polyclonal |
|
Protein full name |
Artemin |
|
Synonyms |
Artn, Enovin, EVN, NBN, Neublastin, Neurotrophic factor |
|
Immunogen |
Recombinant protein corresponding to Mouse Artemin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Rat |
1: 1000-1: 2000 |
cerebellum, striatum |
Background
This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using Artemin (GB113164) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat striatum using Artemin (GB113164) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室