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Anti -S100 beta Mouse mAb
价格：
在线咨询
货号：
KT011583
产品规格：
100 μL
Applications：
IHC/IF
Species：
H,M,R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
S100 beta mouse monoclonal antibody |
|
Protein full name |
Protein S100-B |
|
Synonyms |
S100B, NEF, S100, S100-B, S100beta,S100 calcium binding protein B, S100β |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100B |
|
Isotype |
IgG1 |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm |
|
Uniprot ID |
P50114, P04631, P04271 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1: 1000-1: 2000 |
brain, glioma |
Background
S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS, it acts as a neurotrophic factor and neuronal survival protein. In the adult organism. it is usually elevated due to nervous system damage, which makes it a potential clinical marker.
Images
|
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Immunohistochemistry of paraffin embedded human glioma using S100B (GB12359) at dilution of 1: 1000 (400x lens)
|
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Immunohistochemistry of paraffin embedded mouse brain using S100B (GB12359) at dilution of 1: 1000 (400x lens) |
|
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Immunohistochemistry of paraffin embedded rat brain using S100B (GB12359) at dilution of 1: 1000 (400x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室