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Anti -IL-2 Receptor alpha Rabbit pAb
价格：
在线咨询
货号：
DRF101696
产品规格：
100 μL
Applications：
Species：
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
IL-2 Receptor alpha rabbit polyclonal |
|
Protein full name |
Interleukin-2 receptor subunit alpha |
|
Synonyms |
IL2RA, CD25, IDDM10, IL2R, TCGFR, p55, IMD41, interleukin 2 receptor subunit alpha |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL2RA |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Membrane |
|
Predicted MW. |
31 kDa |
|
Observed MW. |
45 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
splenitis, spleen, lymph gland, thymus |
|
IHC |
Mouse, Rat |
1: 200-1: 1000 |
pneumonia, spleen |
|
IF |
Mouse, Rat |
1: 250-1: 500 |
pneumonia, spleen |
Background
IL-2Rα(Activated T cells IL-2Rα Chain 55), also kown as membrane interleukin-2 receptor (mIL-2R) or CD25, is a protein encoded by IL2RA gene in Human. This protein is 55 kDa which is the high affinity composition of IL-2R. Few IL-2α chains will express in inactive T cells, while the expression will remarkably increase followed by IL-2 accumulation, when T cell surface receptor (TCR) is active. IL-2αchains will become soluble interleukin-2 receptor (sIL-2R) when they are detached from cell membrane into serum, and the molecular weight of sIL-2R is 45 kDa. The concentration of sIL-2R in serum can be used for a mark to measure T cells activation and IL-2Rα chains expression.
Images
|
Western blot analysis of IL2RA (GB11612) at dilution of 1: 1000 Lane 1: Jurkat cell lysate Lane 2: Mouse splenitis tissue lysate Lane 3:Mouse spleen tissue lysate Lane 4: Mouse lymph gland tissue lysate Lane 5: Mouse thymus tissue lysate Lane 6: Rat splenitis tissue lysate Lane 7: Rat spleen tissue lysate Lane 8: Rat lymph gland tissue lysate Lane 9: Rat thymus tissue lysate
|
|
Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using IL2RA (GB11612) at dilution of 1: 500
|
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using IL2RA (GB11612) at dilution of 1: 500
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室